APE/CECD (APS-1) SYNDROME

APS Type 1.org

WELCOME! If you've found this site, either you or someone you know or love has been recently diagnosed with a rare disease called Autoimmune Polyglandular Syndrome Type 1 (APS Type 1) also known as (APECED) Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy.

Jeanette’s APECED (APS-1) Home Page

My vision is to link families and health professionals with sound and empowering information

and with each other, to help maximize the quality of life for people with APECED (APS1).

Welcome to DISEASE-RESOURCES.COM

Web Site information on various medical problems

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HYPER-PARATHYROIDISM

Hyperparathyroidism (Published with permission

Primary hyperparathyroidism is a disorder of the parathyroid glands. Most people with this disorder have one or more enlarged, overactive parathyroid glands that secrete too much parathyroid hormone.

Hyperparathyroidism

Hyperparathyroidism is a condition in which the parathyroid glands (not the thyroid glands!) produce too much parathyroid hormone.

Preoperative Localization of Parathyroid Tumors

If you have parathyroid disease, chances are that just one of your parathyroid glands has gone bad. Parathyroid disease will be cured if the surgeon takes out that one bad gland!

Hyper-Parathyroidism (published with permission)

Parathyroid glands go bad in one way...they make too much parathyroid hormone. This page of Parathyroid.com discusses what happens when you have too much parathyroid hormone and develop hyperparathyroidism. Parathyroid Disease is called "Hyperparathyroidism".

Parathyroid Surgery: The Standard Techniques

Since 1925, the gold standard treatment for primary hyperparathyroidism has been to surgically remove the parathyroid gland (or glands) which are overproducing hormone.

PARATHYROID

The four small parathyroid glands are located at the front and base of the neck at the 4 corners of the thyroid gland (Figure 1.). They are normally the size of a grain of rice.

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HYPOPARATHYROIDISM

Generalized pustular psoriasis with hypoparathyroidism (Published with permission)

A 36-year-old Japanese woman with pustular psoriasis associated with hypoparathyroidisum was reported. The patient showed hypocalcemia and was treated with calcium supplements and calcitriol. When the serum calcium level became normal, the pustules disappeared and erythroderma completely resolved.

Hypoparathyroidism (published with permission)

Hypoparathyroidism is the combination of symptoms due to inadequate parathyroid hormone production (Hypo-parathyroid-ism). 

Hypoparathyroidism (Published with permission)

A hormone called parathyroid hormone (PTH) regulates the amount of calcium and phosphorus in bone and blood. Four small glands called parathyroid glands make PTH. The parathyroid glands are located behind the thyroid gland in the neck.

Tetany  (Published with permission)

Tetany, condition of mineral imbalance in the body that results in severe muscle spasms. Tetany occurs when the concentration of calcium ions (Ca++) in extracellular fluids such as plasma falls below normal.

A hypocalcemic child with a novel activating mutation of the calcium-sensing receptor.  (Published with permission)

Persistent hypercalciuria, with the attendent risk of nephrocalcinosisand eventual renal failure, is common in hypoparathyroid patients, ...

Psychiatric Aspects of Parathyroid Disease (Published with permission)

Parathyroid diseases can present with psychiatric symptoms and can be recognized through determinations of serum electrolytes, especially the calcium level.

Hypocalcemia (Published with permission)

Hypocalcemia, like hypercalcemia, may vary from a very mild and asymptomatic biochemical abnormality to a severe life-threatening disorder depending on the duration, severity, and rapidity of development. The causes of hypocalcemia (Table 1) are either from increased loss of calcium from the circulation or from insufficient entry of calcium into the circulation.

Calcium Metabolism and Osteoporosis Program, American University of Beirut Medical Center, Lebanon

The Calcium Metabolism and Osteoporosis Program at the Endocrine Division of AUBMC has the following mission: promote excellence in clinical care, research and education in disorders of calcium and bone metabolism.

How the Body Works : The 4 Parathyroid Glands

YouTube Animation about how the parathyroid glands work.

EFF Metabolic Bone Disorder Preceptorship - Dr. Mishaela Rubin

Dr. Mishaela Rubin at Columbia University May 2006  Video presentation-  This is really quite good!

Hypoparathyroidism  (Published with permission)

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

Hypoparathyroidism by Dolores Shoback, M.D.

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 HYPOPARATHYROIDISM – TREATMENT AND MANAGEMENT

Calcitriol (Published with permission)

General information about Calcitriol.  This is for veterinary use only but might also contain useful information for our two legged friends.)

Parathyroid Surgery: The Standard Techniques

( Published with permission)

Since 1925, the gold standard treatment for primary hyperparathyroidism has been to surgically remove the parathyroid gland (or glands) which are overproducing hormone.

Rocatrol (Published with permission)

Clinical information about Rocaltrol from Drug flier.

Vitamin D Deficiency And Dependency

You can type the topic you are interested in in the "SEARCH" block on this page.  Other information is also available

Vitamin D (Cholecalciferol, Calcitriol)  (Published with permission)

Vitamin D is a steroid hormone that has long been known for its important role in regulating body levels of calcium and phosphorus, and in mineralization of bone.

Rx List:  The Internet Drug List

http://www.rxlist.com/http://www.rxlist.com/

Proton-Pump Inhibitors and Hypomagnesemic Hypoparathyroidism  (Published with permission)

To the Editor: We report two cases of hypomagnesemic hypoparathyroidism associated with the use of proton-pump inhibitors, in which patients presented with carpopedal spasm in association with severe hypomagnesemia and hypocalcemia without an appropriate increase in the level of parathyroid hormone.

PREOS(R) Granted U.S. Orphan Drug Status for Treatment of Hypoparathyroidism  (Published with permission)

NPS Pharmaceuticals, Inc. (Nasdaq: NPSP) announced today that the U.S. Food and Drug Administration's Office of Orphan Products Development has granted orphan drug designation to PREOS(R) (parathyroid hormone [rDNA origin] for injection) for the treatment of hypoparathyroidism, a rare deficiency of parathyroid hormone for which there is no FDA-approved therapy.

Got Milk? A new theory on the relationship between calcium and PMS  (Published with permission)

Premenstrual Syndrome (PMS) has been described as one of the most common disorders in females, afflicting millions of premenopausal women.

Calcium and PMS (Published with permission)

If you're a woman who suffers from Premenstrual Syndrome (PMS) or a man who suffers with a woman who suffers, you'll be interested in this month's column. All you need to do is eat more yogurt, an excellent source of calcium, and your symptoms will improve or go away! It won't happen overnight, but with regular consumption of a diet high in calcium for at least two months, your PMS will lessen.

Dr. Nasreen Sayed Discusses Her treating Hassan Fadhul for hypoparathyroidism in Bahrain

Dr. Sayed is a physician in Bahrain who has been treating Hassan Fadhul for the past couple of years.  Hassan has been on Forteo and has had quite a story.  I hope you will benefit from what Dr. Sayed has to say of her experiences.

Factors that inhibit calcium absorption (published with permission)

We focus on supplementing our diets with calcium, but we don't stop to….

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